Three-dimensional (3D) substrates, such as 3D scaffolds and 3D hydrogels, serve as mechanical platforms for cell attachment and growth. Biomaterials with viscoelastic supports that can continuously adapt to external constraints and respond to many physiological stimuli are designed to mimic the organic environment of cells. The 3D matrix allows cells to be grown in vitro in a more natural way. Different from 2D cells, the microenvironment of cell growth in 3D cell model is almost close to that in the body, which can truly reflect the interaction between cells in the body, cells and matrix, cells and microenvironment, and to a certain extent reproduce the process of disease occurrence and development. In the last decade, it has been proposed that genetically modified cells grown or embedded on 3D substrates can be used as controlled drug release systems. 3D substrates can be made of a variety of materials (collagen, ectopic collagen, polymers, hyaluronic acid, fibrin...).
CD Bioparticles' services with customized delivery strategies, precise designs and modifications of drugs or drug-contained cargos, and advanced technical platforms can help you to solve:
Drug Delivery Nanoparticles Formulation
Bioparticles Analysis and Characterization
Bioactive Particles & Fillers Production
Functional Biomedical Coatings