Bioparticles Analysis and Characterization

• Bioparticle Component Analysis
• Bioparticle Size and Morphology Analysis
• Drug In Vitro Testing
• Drug Localization Analysis
• Bioparticles Encapsulation Efficiency Analysis
• Lamellarity Determination
• Bioparticles Penetration and Permeation Test
• Pharmacodynamics and Pharmacokinetics Test
• Bioparticles Stability Studies
• Toxicity Measurement
• Bioparticles Zeta Potential Analysis
• In Vivo Fates Prediction Study

CD Bioparticles’ services of wide coverage of Bioparticles Analysis and Characterization, and advanced metrology platforms can help you to solve:

The challenges you might meet:

• High complexity of the drug delivery bioparticle forms including dispersions, powders, and microcapsules requiring several methods for analysis and characterizations
• Lack of experiences of drug delivery system so that having no idea which technique to use
• Low quality and low accuracy of results
• Concerns about less-than-optimal techniques only available in-house

Key features:

• Toxicity Measurement
  • In Vitro Assessment Assays
    • DNA synthesis
    • DNA damage
    • Altered gene expression
    • Immunogenicity
    • Oxidative stress
    • Cell proliferation
    • Exocytosis
    • Metabolic activity
    • Hemolysis
    • Apoptosis and necrosis
  • In Vitro Assessment Assays
• Drug In Vitro Testing
  • In vitro drug release
  • In Vitro Toxicity Test
  • In Vitro Drug Sensitivity Tests
• Lamellarity Determination
  • ³¹P- nuclear Magnetic Resonance (NMR)
  • Small Angle X-ray Scattering (SAXS)
  • Cryo-electron Microscopy
• Drug Localization Analysis
  • Plasma Protein Binding
  • Brain Tissue Binding
  • Microsomal Binding
• Bioparticles Stability Studies
  • Analysis of Bioparticle Size and Morphology
  • Self-association (Agglomeration/Aggregation) Analysis
  • Analysis of Surface Charge Change
  • Analysis of Changes in Dissolution/Release Rate of Active Ingredients
• Bioparticle Component Analysis
  • X-ray Diffraction (XRD)
  • Liquid Chromatography-mass Spectrometry (LC-MS/MS)
  • Raman Spectroscopy
• Bioparticles Zeta Potential Analysis
• Bioparticle Size and Morphology Analysis
  • Dynamic Light Scattering (DLS)
  • Scanning Electron Microscopy (SEM)
  • Transmission Electron Microscope (TEM)
  • Atomic Force Microscopy (AFM)
• Pharmacodynamics and Pharmacokinetics Test
  • Microscale Thermophoresis
  • Mass Spectrometry
• Bioparticles Penetration and Permeation Test
  • Dermal Absorption Test
  • Parallel Artificial Membrane Permeability Assay (PAMPA)
  • Caco-2 Permeability
• Bioparticles Encapsulation Efficiency Analysis

Key benefits:

• Bulk Analysis and Characterization services including descriptive data analysis
• Our long-term experience and advanced metrology platforms can help you determine and optimize the most applicable technique, or the combination of techniques to solve your problem
• We can help you to optimize an experiment based on the most cost-effective strategies and provide you the deep data analysis based on descriptive and inferential statistics. . We will help you to know your materials better and provide you the solutions to solve your problems from every aspect.
• The quality and accuracy of analysis results are taken seriously. The design of experiments follows the principles of statistics
• Quick turnaround time
• No concerns about the scale of analysis. Analysis ranging from one-sample request to large-scope or multiple runs are all acceptable
• We offer customized analysis strategies and protocols development

If you don't see what you need, or don't know what you need, give us a call at 1-631-624-4882 or email , and our team will work with you to find the right solution for your analysis.