Acyl Carnitine Lipids

Acyl Carnitine Lipids, also known as acylcarnitines, are a class of lipids that play a crucial role in energy metabolism. They are formed when long-chain fatty acids are bound to carnitine, a small molecule that transports fatty acids from the cytosol into the mitochondria for beta-oxidation, the process of breaking down fatty acids to produce energy. Acylcarnitines are synthesized in the liver and transported via the bloodstream to other tissues, where they are taken up by the mitochondria and used for energy production. They serve as important markers for mitochondrial dysfunction and metabolic disorders such as fatty acid oxidation disorders and diabetes. Measurement of acylcarnitine levels in blood or tissues can provide valuable information about fatty acid metabolism and energy production, and can help in the diagnosis and management of metabolic disorders.

CD Bioparticles' services with customized delivery strategies, precise designs and modifications of drugs or drug-contained cargos, and advanced technical platforms can help you to solve:

The challenges you might meet:

• Many chemicals cannot breach the blood-brain barrier to treat brain diseases
• The lipid metabolism pathway of various regulatory factors is not clear
• Oxidative damage impairs the integrity of liver cells and thus affects lipid metabolism
• Tedious liposome formulation, purifications, and production

Key benefits:

• Surface active liposomes allowing the modification of the drug-loaded liposomes to achieve cell-targeting or tissue-targeting
• Remove toxic long-chain fatty acids from cells
• Improve mitochondrial function and motor capacity
• Simple operation, selective, low cost
• Suitable for in vitro and in vivo experiments
• Ready-to-use

Application candidates:

• To treat heart disease
• As a biomarker to diagnose and monitor the progression of obesity and diabetes
• To treat Alzheimer's disease, depression and neuropathic pain
• Diagnosis and management of metabolic disorders
• To study the disorders associated with lipid metabolism