Agonists


Agonist lipids are a type of lipid molecule that can bind to and activate a specific type of receptor called a G protein-coupled receptor (GPCR). These lipids can initiate cellular signaling pathways that can result in diverse physiological responses such as hormone secretion, smooth muscle contraction, and inflammation. Examples of agonist lipids include prostaglandins, leukotrienes, and thromboxanes. These lipids are important in various biological processes such as inflammation, pain, and fever, and can also be targeted for therapeutic purposes.

CD Bioparticles' services with customized delivery strategies, precise designs and modifications of drugs or drug-contained cargos, and advanced technical platforms can help you to solve:

The challenges you might meet:

  • The structure of the agonist lipids receptor is diverse
  • The lipid metabolism pathway of various regulatory factors is not clear
  • The effects of agonist lipids can be context-dependent
  • Some cancers are difficult to treat directly with chemicals
  • Tedious liposome formulation, purifications, and production

Key benefits:

  • Surface active liposomes allowing the modification of the drug-loaded liposomes to achieve cell-targeting or tissue-targeting
  • Activate cell signaling pathways
  • Simple operation, selective, low cost
  • Suitable for in vitro and in vivo experiments
  • Ready-to-use

Application candidates:

  • To treat acute and chronic inflammation
  • Research on vaccine
  • Tumor immunotherapy
  • To treat pulmonary arterial hypertension and prevent blood clots
  • To improve overall brain health by providing neuroprotection
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GRI-977143 CDFCB042 Powder 5 mg INQUIRY
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Kdo2-Lipid A (KLA) CDLP-A571 Powder 1 mg INQUIRY
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Lysophosphatidic acid (Oleyl form) CDFCB040 Powder 5 mg INQUIRY
MK-571 CDFCB038 Powder 5 mg INQUIRY
NA-Gly CDFCB036 Powder 10 mg INQUIRY
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Oleoylethanolamide CDFCB035 Powder 10 mg INQUIRY
Palmitoylethanolamide CDFCB034 Powder 20 mg INQUIRY
Prostaglandin E2 CDFCB002 Powder 1 mg INQUIRY
Synaptamide CDFCB015 Oil 5 mg INQUIRY
TG 4-155 CDFCB030 Powder 5 mg INQUIRY
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