Fatty Acid Modified Lipids

The release of an active drug is critical to its activity, altering its efficacy, pharmacokinetics, tissue distribution, and side effects. Fatty acid modified lipids can help build a prodrug system, improve the water solubility and encapsulation rate of anti-tumor drugs, enhance the retention time of drugs in vivo, and reduce drug toxicity and side effects. Fatty acid modified lipids have been widely used in anti-tumor drug delivery and in the synthesis of surfactants and their intermediates.

CD Bioparticles’ services with customized delivery strategies, precise designs and modifications of drugs or drug-contained cargos, and advanced technical platforms can help you to solve:

The challenges you might meet:

  • Lipids delivery models are unstable of thermodynamics in vitro or in vivo studies
  • Small-molecule antitumor drugs have poor solubility
  • Antitumor drugs usually have more toxic side effects
  • Drugs metabolize too quickly in vivo resulting in insufficient retention time
  • The concentration of the drug at the tumor site is low
  • Tedious liposome formulation, purifications, and production

Key features:

Key benefits:

  • Improve the hydrophilicity of the drugs contained
  • Improve the absorption, distribution and metabolism of active drugs in vivo
  • Increase the stability and encapsulation rate of the drugs contained
  • Reduce the toxicity and side effects of drugs and improve their efficacy
  • Simple operation, selective, low cost
  • Suitable for in vitro and in vivo experiments
  • Ready-to-use

Application candidates:

  • To deliver antitumor drugs
  • Synthesize and produce various surfactants and their intermediates
  • Study on lipidase
  • As high affinity ligands or agonists
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