Adhesive Lipids

Adhesive lipids prolong the retention time of the particles in the body, and the encapsulated drugs can be slowly released from the skeleton, thus improving the bioavailability. Adhesive lipids can also be used to analyze various metal ions and biomolecules via colloidal behavior and optical transformations. Natural non-irritating substances with high hydrophobicity, adhesion, and pseudoplasticity help to improve the retention time of the modified carriers on the ocular surface, thus improving the drug utilization rate.

CD Bioparticles' services with customized delivery strategies, precise designs and modifications of drugs or drug-contained cargos, and advanced technical platforms can help you to solve:

The challenges you might meet:

• The drug has poor membrane penetration and is difficult to pass through the eye barrier
• Drugs have a short half-life and are easily metabolized in the body
• Oral bioavailability of the drug in vivo is low
• The drug has a large toxic side effect, will kill non-target healthy cells
• It is difficult for drugs and carriers to form well-organized colloidal or spherical structures in aqueous environment
• The concentration of the drug at the tumor site is low
• Tedious liposome formulation, purifications, and production

Key benefits:

• Increase efficacy and therapeutic index of the entrapped drug
• Increase the half-life and bioavailability of the drug
• Easy to metabolize and less toxic
• The structure is flexible and can be coupled with site-specific ligand to achieve active targeting
• Improved stability over other drug solubility vehicles
• Suitable for in vitro and in vivo experiments
• Ready-to-use

Application candidates:

• Applied to colorimetric sensing platform
• For the treatment of eye diseases
• For the treatment of acute coronary syndrome
• To measure cell viability