N-Acylglycine (NAGly)

N-Acylglycine (NAGly) is a naturally occurring metabolite. NAGly is derived from fatty acids and glycine and is known to activate a specific receptor in the body, called GPR18. This receptor is found in various tissues throughout the body, including the brain, immune system, and cardiovascular system. Research has suggested that NAGly may have anti-inflammatory and analgesic properties, making it a potential treatment option for conditions such as chronic pain and inflammation. Additionally, studies have shown that NAGly may have neuroprotective effects and could potentially be used to treat neurodegenerative diseases such as Alzheimer's and Parkinson's. Despite the promising potential of NAGly, further research is needed to fully understand its mechanisms of action and potential therapeutic uses.

CD Bioparticles’ services with customized delivery strategies, precise designs and modifications of drugs or drug-contained cargos, and advanced technical platforms can help you to solve:

The challenges you might meet:

• Some inflammation will develop into cancer without intervention treatment
• Chemical anticancer drugs have great toxic and side effects on normal cells
• Some drugs have a low solubility in human body fluids
• Drug concentration and bioavailability in target tissues are low
• Tedious liposome formulation, purifications, and production

Key benefits:

• Anti-inflammatory properties allow it to target specific tissues
• To increase the solubility and bioavailability of the target drug
• Deliver drugs directly to the target tissue, reducing the risk of side effects
• High purity, less experimental dosage
• Suitable for in vitro and in vivo experiments
• Ready-to-use

Application candidates:

• Research and development of analgesic and anti-inflammatory drugs
• Potential additives for fertilizers and other agricultural products
• To help protect crops from harmful pathogens and pests
• Targeting specific tissues as a drug delivery vehicle