Phospholipids


Phospholipids have excellent biocompatibility and significant amphiphilic properties, which make phospholipids major and suitable agents or excipients in pharmaceutical preparations and enable better therapeutic applications in drug delivery systems. CD Bioparticles' services with customized delivery strategies, precise designs and modifications of drugs or drug-contained cargos, and advanced technical platforms can help you to solve:

The challenges you might meet:

  • Phospholipid deposition exacerbates the adverse effects of the drug
  • The phospholipid ratio of the drug loading formula is not ideal
  • The bioavailability of lipophilic drugs and drugs with low membrane permeability is low
  • The absorption and release of drugs are blocked
  • The side effects and bitter taste of drugs are hard to accept
  • Sensitive active agents are easily degraded in vivo
  • The dose of drug needed for treatment is too high and the release rate is too fast

Key features:

Key benefits:

  • Wide coverage of pre-formulated drug-loaded phospholipids
  • Surface active phospholipids allowing the modification of the drug-loaded liposomes to achieve cell-targeting or tissue-targeting
  • Post-drug-loading phospholipids allowing customized drug loading
  • Enhanced aqueous solubility of water insoluble compounds
  • Improved stability over other drug solubility vehicles
  • Suitable for in vitro and in vivo experiments
  • Ready-to-use

Application candidates:

  • Avoid drug-induced liver injury
  • Improve the bioavailability of drugs with low water solubility and low membrane permeability
  • Improve drug absorption and release properties
  • Protect sensitive active agents from degradation in the GIT tract
  • Reduce the side effects of drug
  • Mask the bitter taste of the drug
  • Phospholipids have significantly greater clinical benefit

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