PAF & PAF Analogs

Platelet-activating factor (PAF) stands as a lipidic cohort of chemical mediators that perform critical biological functions, both in human physiology and pathology, through an intricate interplay between a diverse range of cells, including but not limited to platelets, neutrophils, monocytes, lymphocytes, basophils, eosinophils, mast cells, and endothelial cells. The multifarious roles of PAF encompass a wide spectrum of physiological and pathological phenomena, including reproduction, memory, vascular tone, apoptosis, angiogenesis, inflammation, asthma, atherosclerosis, diabetes, renal diseases, cancer, HIV, and periodontitis. Excess levels of PAF have been linked to various pathologies and disorders, prompting the study of PAF inhibition as a possible therapeutic intervention for mitigating these conditions. Initially, PAF referred to a single phosphoglycerylether lipid containing between 16 and 18 carbons, but now encompasses a myriad of PAF-like molecules.

CD Bioparticles manufactures and supplies PAF & PAF analogs for lipid system research. Contact us to find out how PAF & PAF analogs can help your work.