PC & LPC

Phosphatidylcholine (PC) was first discovered in egg yolk and was originally called “lecithin”. It is the most common phospholipid in cells and helps incorporate cholesterol into membranes. The creation of sphingomyelin also relies on its PC precursor. PC has been associated with various biological functions, including intracellular cholesterol transport and membrane cholesterol regulation. It also helps with membrane-mediated cell signaling and activating enzymes through PCTP.
Lysophosphatidylcholine (LPC) has been increasingly linked to cardiovascular and neurodegenerative diseases. LPC is mainly produced by breaking down PC through an enzyme called phospholipase A2. LPC can be recycled back to PC when Acyl-CoA is available and lysophosphatidylcholine acyltransferase (LPCAT) is present. Scientists are currently studying enzyme kinetics and LPC metabolism to discover possible treatments for LPC-related diseases.

CD Bioparticles manufactures and supplies short chain (C3-C8 are water soluble and hygroscopic), saturated, multi-unsaturated and mixed acid PC for lipid system research. Contact us to find out how PC& LPC can help your work.