PS & LPS

CD Bioparticles, an industry leader in innovative drug delivery solutions, is currently offering a cutting-edge array of phosphatidylserine (PS) and lipopolysaccharide (LPS) products that have exhibited exceptional biocompatibility and demonstrated unparalleled effectiveness as carriers for drug delivery. PS, a ubiquitous phospholipid that constitutes nearly 15% of the total phospholipid in the human cerebral cortex and retina, is also present in various organelle membranes, with the highest concentration recorded in endosomes and plasma membranes but comparatively low in mitochondria, especially mitochondrial inner membranes. Interestingly, PS is asymmetrically distributed across the bilayer, with a higher concentration in the inner layer compared to the outer layer, reflecting its critical role in maintaining cellular homeostasis. The dynamic redistribution of PS in response to diverse physiological cues, such as during the blood clotting cascade or early apoptosis, underscores its indispensable role in a myriad of cellular processes.

Conversely, LPS, a derivative of PS, contains a fatty acid on either side of the glycerol backbone and is emerging as a key lipid mediator in various pathological conditions, including neurodegenerative and autoimmune diseases. The versatility and potency of LPS as a drug delivery vehicle are only beginning to be explored, and CD Bioparticles is at the forefront of harnessing its immense potential for next-generation therapeutic interventions.