Sterols

Based on hydrophilic and lipophilic properties of sterols, they are able to achieve long circulation applications in vivo, improve cell membrane rigidity, and construct drug delivery systems in vivo and in vitro. CD Bioparticles' services with customized delivery strategies, precise designs and modifications of drugs or drug-contained cargos, and advanced technical platforms can help you to solve:

The challenges you might meet:

• Biomembrane has too much fluidity and lack structural rigidity for in vitro and in vivo studies
• Complicated formulation of the drug-loaded liposomes with optimized loading yield of different drug molecules
• The loading rate of hydrophilic drugs is low
• Strong immune response or foreign body response of your materials
• Tedious drug-loaded liposome formulation, purifications, and production

Key features:

• Oxysterols Oxidized derivative of sterols
• Bile acids Steroid acid
• Natural Sterols Natural plant sterols
• Oxidized Sterols
• Cholesteryl Esters Product of fatty acids and alcohols
• Glycosylated Sterols

Key benefits:

• Surface active liposomes allowing the modification of the drug-loaded liposomes to achieve cell-targeting or tissue-targeting
• Post-drug-loading liposomes allowing customized drug loading
• Enhance the lipid solubility of water-soluble drugs
• Improved stability over other drug solubility vehicles
• Increase the rigidity and drug loading of liposomes
• Suitable for in vitro and in vivo experiments
• Ready-to-use

Application candidates:

• Drug delivery models of in vitro or in vivo studies
• Long circulation applications
• Cell-targeting or tissue targeting drug delivery
• Studies on antioxidant products
• Research on drugs to improve liver function