In the realm of drug delivery, the utilization of Multi-Alkyne Organic Covalent Organic Frameworks (COFs) linkers has emerged as a promising avenue for enhancing therapeutic outcomes. These unique molecular structures exhibit a high degree of porosity and tunable physicochemical properties, allowing for precise control over drug encapsulation and release. The multi-alkyne functionality of these COF linkers offers a versatile platform for the design of drug delivery systems with improved stability and sustained release profiles. By capitalizing on the robust covalent bonds within the framework, these linkers provide a stable matrix for encapsulating therapeutic agents, safeguarding against premature drug release. Furthermore, the modular nature of multi-alkyne COFs facilitates tailored adjustments to accommodate diverse drug payloads.
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