DOTAP Liposomes

DOTAP liposomes are a type of liposome, which are spherical vesicles composed of a lipid bilayer membrane that can encapsulate and deliver various types of drugs or molecules. DOTAP stands for "1,2-Dioleoyl-3-trimethylammonium-propane," which is a positively charged lipid commonly used in the formulation of cationic liposomes. ationic liposomes, such as those containing DOTAP, have a positively charged surface that can interact with negatively charged molecules, such as DNA or RNA, to form complexes known as lipoplexes. These lipoplexes can be used for gene delivery, as the cationic surface of the liposomes can interact with the negatively charged phosphate groups of DNA or RNA to facilitate their uptake into cells.

In addition, DOTAP liposomes can also be used for drug delivery, as they can encapsulate hydrophobic drugs within their lipid bilayer membrane or hydrophilic drugs within their aqueous interior. The positive charge on the surface of the liposomes can also help to improve the uptake of the liposomes by cells and increase the effectiveness of the delivered drug.

CD Bioparticles manufactures and supplies DOTAP liposomes for drug delivery research. Contact us to find out how DOTAP liposomes can help your work.