Fluorescent Polymers

CD Bioparticles’ products with deep understanding of the strategies and the applications of various of delivery cargos with precise designs and advanced technical platforms can help you to solve:

The challenges you might meet:

• Hard to track and image the distribution of the polymer based (nano-)materials
• Limited wavelength coverage for your tracking and detection experiments
• Issue of quenching or fluorescence compensation
• Non-active fluorescent polymers which cannot be conjugated with other molecules
• Tedious chemical synthesis, formulation, and purifications

Key Features

• Fluorescent Dextrans
  • Mw ranges from 6 kDa to 2000 kDa
  • Additional functional group useful for further conjugation and modification
• Fluorescent Chitosans
• Fluorescent Lipid PEGs
  • Biocompatible and fluorescent building blocks of nanostructures
  • Useful for visualizing the post-PEGylation of liposomes
• Fluorescent Polylactides
• Fluorescent Triblock Copolymers
  • Biocompatible and fluorescent building blocks of nanostructures
• Fluorescent AB Diblock Copolymers
  • Terminal modified fluorophore
  • Useful to visualize the nano-assembly
• Fluorescent Monodispersed Linear PEGs
• Fluorescent Poly(lactic-co-glycolic acid)s
• Fluorescent Heterobifunctional Linear PEGs
• Fluorescent options:
  • DiA (ex/em: 456/590 nm), DiD (ex/em: 644/665 nm), DiI (ex/em: 549/565 nm), DiO (ex/em 484/501 nm), DiR (ex/em: 750/780 nm), NBD headgroup tagged lipid (ex/em: 460/535 nm), NBD fatty acid tail tagged lipid (ex/em: 460/534 nm), rhodamine headgroup tagged lipid (ex/em: 560/583 nm) , dansyl headgroup tagged lipid (ex/em: 336/513 nm) and pyrene headgroup tagged lipid (ex/em: 351/379 nm)

Key benefits:

• Multi-functional groups for further-modifications and labeling purpose
• Wide coverage of the fluorophores and the wide coverage of the molecular weight of the polymers
• Consistent reaction efficiency of the functionalized fluorescent polymers
• Precise control of the fluorophore substitution, well-control of the intensity-concentration dependence

Application candidates:

• Fluorescent nanoparticle/scaffold/hydrogel preparation
• Tracking and detection of cell uptake (e.g. macrophage)
• Able to conjugate with biomolecules for cell-specific and tissue-specific targeting, tracking, and detecting
• PK/PD analysis