Liposome System

CD Bioparticles’ products with customized delivery strategies, precise designs and modifications of drugs or drug-contained cargos, and advanced technical platforms can help you to solve:

The challenges you might meet:

  • Limited options of drug-loaded or non-loading liposomes for positive control and negative control of your drug delivery tests or exosome studies
  • Complicated formulation of lipid composition and ratio to prepare artificial cell models
  • Hard to incorporate active biomolecules, such as peptide, antibody, protein, nucleic acid, and polysaccharide on the surface of the liposomes
  • Limited options for tracking and detection of fusion, pore forming, and cell uptake (e.g. macrophage) experiments
  • Hard to track and image the distribution of the liposomes
  • Tedious chemical synthesis, formulation, and purifications

Schematic representation of the classification of different liposomes. Figure 1. Schematic representation of the classification of different liposomes.

Plain Liposomes Key features:

  • Plain Liposomes

    • DOTAP-based Cationic Liposomes

    • Total Lipid Liposomes from Natural Lipid Extracts

    • Phosphatidylserine (PS) Liposomes

    • Cardiolipin Lipids (CL) Liposomes

    • Phosphatidylcholine (PC) Liposomes

    • Phosphatidylglycerol (PG) Liposomes

  • Reactive Liposomes

    • Folate Liposomes

    • Cyanur Liposomes

    • Succinyl Liposomes

    • Glutaryl Liposomes

    • Amine Liposomes

    • Carboxylic Acid Liposomes

    • Metal Chelating Liposomes: Ni Reactive Liposomes:

    • Biotinylated Liposomes

    • Dodecanyl Liposomes:

    • Azide Liposomes

    • DBCO Liposomes

    • PDP Liposomes: Sulfhydryl Reactive Liposomes

  • Magnetic Liposomes

  • Fluorescent Liposomes

    • Fluorescent Plain Liposomes

    • Fluorescent Reactive Liposomes

    • Fluorescent Drug Loaded Liposomes

    • Fluorescent Liposomes for DNA/RNA Delivery

    • Wide coverage of the Fluorescent options

  • Drug Loaded Liposomes

    • Liposomal ATP

    • Liposomal DOTA

    • Liposomal Topotecan

    • Liposomal Clodronate

    • Liposomal Doxorubicin

    • Liposomal Alendronate

  • Liposomes for Cosmetics

    • Resveratrol

    • THC

    • Vitamin A Palmitate

    • Vitamin C

    • Curcumin

    • Alpha Lipoic Acid

    • Vitamin A, E & K

    • Coenzyme Q10

    • Azelaic Acid

    • Soy Isoflavones

    • Phenylethyl Resorcinol

    • Vitamin E

    • Ferulic acid

    • Phytosterol

    • Lutein

    • Salicylic acid

    • Retinaldehyde

    • Ceramide

  • API loaded Liposomes

    • Food additives

      • Vitamine A liposomes
      • Alpha lipoic acid (ALA) liposomes
      • Curcumin liposomes
      • AEK liposomes
      • HK20 liposomes
      • Ferulic Acid liposomes
      • Asta liposomes
      • Q10 liposomes
      • Resveratrol liposomes
      • Lutein liposomes
      • Vitamine E liposomes
      • ISO (Estradiol) liposomes
      • Vitamine C liposomes
    • Cosmetic additives

      • 4-Hexylresorcinol liposomes
      • Retinol liposomes
      • Idebenone liposomes
      • r-Retinoate liposomes
      • Liposomal o-Cymen-5-OL
      • Liposomal Asta
      • Liposomal Resveratrol
      • Liposomal THC
      • Liposomal Vitas
      • Liposomal Pterostilbene
      • Liposomal Gallic acid
      • Natural Soluble Yeast Beta-Glucan
      • Phytosterol liposomes
      • Azelaic liposomes
      • Liposomal 377
      • 5-amino-4-oxovaleric acid
      • Galla Rhois Gallnut Extract Nanoemulsion
      • Salicylic Acid liposomes
      • Anti-acne concentrates liposomes
  • Liposomes for DNA/RNA Delivery

    • DDAB Liposomes for DNA/RNA Delivery

    • GL-67 Liposomes for DNA/RNA Delivery

    • DOTMA Liposomes for DNA/RNA Delivery

    • DOTAP Liposomes for DNA/RNA Delivery

    • DODAP Liposomes for DNA/RNA Delivery

    • DC-Cholesterol Liposomes for DNA/RNA Delivery

Plain Liposomes Key benefits:

  • Wide coverage of the functional liposomes
  • Cell-membrane mimic liposomes
  • Multi-functional-group useful for further conjugation and crosslinking, good for further conjugation, labeling, targeting
  • Wide coverage of fluorescent lipophilic tracer for tracking and detection of the liposomes
  • Precise control of the fluorophore substitution, well-control of the intensity-concentration dependence
  • Optimized liposome composition improving transfection efficiency and stability
  • Fluorescent cationic liposome useful tracking and imaging of the transfection
  • Post PEGylation useful for optimizing the PEG ratio
  • Pre-loaded API liposomes useful for various of formulations and studies
  • Ready-to-use

Plain Liposomes Application candidates:

  • Control formulations for many different types of drug encapsulated liposome formulations.
  • Artificial cell models
  • Charged liposomes useful in many different types of blood complement studies
  • Tracking and imaging of the transfection
  • DNA/RNA delivery
  • Fusion experiments of two separate membranes.
  • Tracking and detection of cell uptake (e.g. macrophage)
  • Long circulation applications
  • Experiments that involve pore formation and disruption of the membrane, to study pore formation or disruption by external factors such as detergents, peptides, etc.
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