Val-Cit-alcohol


Val-Cit-alcohol

Val-Cit-alcohol

Catalog:CDAX008

Unit Size:250 mg, 500 mg

INQUIRY Datasheet

Specifications
Common Use Val-Cit-alcohol-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADC). The Val-Cit is specifically cleaved by cathepsin B. As this enzyme is only present in the lysosome the ADC payload will be release only in the cell. The Boc group can be deprotected under acidic conditions to generate a free amine group.
Structure Val-Cit-alcohol
Molecular Weight 274.32
Purity ≥95%
Molecular Formula C11H22N4O4
CAS No. 159858-33-0
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