TCO-PEG1-Val-Cit-PABC-PNP


TCO-PEG1-Val-Cit-PABC-PNP

TCO-PEG1-Val-Cit-PABC-PNP

Catalog:CDAX013

Unit Size:25 mg

INQUIRY Datasheet

Specifications
Common Use TCO-PEG1-Val-Cit-PABC-PNP-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADC). The Val-Cit is specifically cleaved by cathepsin B. As this enzyme is only present in the lysosome the ADC payload will be release only in the cell. The Boc group can be deprotected under acidic conditions to generate a free amine group.
Structure TCO-PEG1-Val-Cit-PABC-PNP
Molecular Weight 811.89
Purity ≥95%
Molecular Formula C39H53N7O12
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