exo-BCN-Val-Cit-PAB-PNP


exo-BCN-Val-Cit-PAB-PNP

exo-BCN-Val-Cit-PAB-PNP

Catalog:CDAX075

Unit Size:25 mg, 50 mg

INQUIRY Datasheet

Specifications
Common Use exo-BCN-Val-Cit-PAB-PNP-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADC). The Val-Cit is specifically cleaved by cathepsin B. As this enzyme is only present in the lysosome the ADC payload will be release only in the cell. The Boc group can be deprotected under acidic conditions to generate a free amine group.
Structure exo-BCN-Val-Cit-PAB-PNP
Molecular Weight 720.77
Purity ≥95%
Molecular Formula C36H44N6O10
CAS No. 2151085-14-0
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