Boc-Val-Cit-PAB-PNP


Boc-Val-Cit-PAB-PNP

Boc-Val-Cit-PAB-PNP

Catalog:CDAX096

Unit Size:100 mg, 250 mg

INQUIRY Datasheet

Specifications
Common Use Boc-Val-Cit-PAB-PNP-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADC). The Val-Cit is specifically cleaved by cathepsin B. As this enzyme is only present in the lysosome the ADC payload will be release only in the cell. The Boc group can be deprotected under acidic conditions to generate a free amine group.
Structure Boc-Val-Cit-PAB-PNP
Molecular Weight 644.67
Purity ≥95%
Molecular Formula C30H40N6O10
CAS No. 870487-10-8
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