BCN-PEG1-Val-Cit-PABC-PNP


BCN-PEG1-Val-Cit-PABC-PNP

BCN-PEG1-Val-Cit-PABC-PNP

Catalog:CDAX107

Unit Size:25 mg, 50 mg

INQUIRY Datasheet

Specifications
Common Use BCN-PEG1-Val-Cit-PABC-PNP-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADC). The Val-Cit is specifically cleaved by cathepsin B. As this enzyme is only present in the lysosome the ADC payload will be release only in the cell. The Boc group can be deprotected under acidic conditions to generate a free amine group.
Structure BCN-PEG1-Val-Cit-PABC-PNP
Molecular Weight 835.91
Purity ≥95%
Molecular Formula C41H53N7O12
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