BCN-PEG1-Val-Cit-PABC-OH


BCN-PEG1-Val-Cit-PABC-OH

BCN-PEG1-Val-Cit-PABC-OH

Catalog:CDAX108

Unit Size:25 mg, 50 mg

INQUIRY Datasheet

Specifications
Common Use BCN-PEG1-Val-Cit-PABC-OH-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADC). The Val-Cit is specifically cleaved by cathepsin B. As this enzyme is only present in the lysosome the ADC payload will be release only in the cell. The Boc group can be deprotected under acidic conditions to generate a free amine group.
Structure BCN-PEG1-Val-Cit-PABC-OH
Molecular Weight 670.81
Purity ≥95%
Molecular Formula C34H50N6O8
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