Azido-PEG3-Val-Cit-PAB-OH


Azido-PEG3-Val-Cit-PAB-OH

Azido-PEG3-Val-Cit-PAB-OH

Catalog:CDAX113

Unit Size:100 mg, 250 mg

INQUIRY Datasheet

Specifications
Common Use Azido-PEG3-Val-Cit-PAB-OH-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADC). The Val-Cit is specifically cleaved by cathepsin B. As this enzyme is only present in the lysosome the ADC payload will be release only in the cell. The Boc group can be deprotected under acidic conditions to generate a free amine group.
Structure Azido-PEG3-Val-Cit-PAB-OH
Molecular Weight 608.7
Purity ≥95%
Molecular Formula C27H44N8O8
CAS No. 2055024-65-0
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