Clipos™ DT-061 (SMAP) Encapsulated Liposomes


Catalog:CDEPG-02

Unit Size:2 mL, 10 mL

INQUIRY Datasheet

Description PEGylated liposomes containing PP2A activator DT-061 (SMAP). DT-061 is an activator of protein phosphatase 2A (PP2A). PP2A regulates many cellular signaling pathways including MAPK/ERK, Wnt/β-catenin, Akt/mTOR, GSK3β, p53/apoptosis, cell cycle, and others. This product can be used in vitro or in vivo for studying the effects of PP2A activation and could be applied to preclinical therapy of KRAS-mutant and MYC-driven tumors. The liposomes are PEGylated for optimal in vivo performance. For preclinical research use only.
Lipid composition PEGylated liposomes
Liposome Size 70-120 nm
Lipid Molar Concentration 60 mM
Encapsulated Drug DT-061
Drug concentration 4.0 mg/mL
Inside Buffer 300 mM sucrose
Outside Buffer 300 mM sucrose
Storage 2 °C to 8 °C (do not freeze)
Shelf-life At least 1 month

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