Clipos™ Rocaglamide Encapsulated Liposomes


Catalog:CDEPG-21

Unit Size:1 mg, 5 mg, 10 mg, 25 mg

INQUIRY Datasheet

Specifications
Description PEGylated liposomes containing Rocaglamide (Roc-A). Rocaglamide is a potent inhibitor of NF-κB activation in T-cells. Rocaglamide is a potent and selective HSF1 activation inhibitor (IC50 ~50 nM). Rocaglamide inhibits the function of the translation initiation factor eIF4A. Rocaglamide also exhibits anti-leukemia activity. Rocaglamide is insoluble in aqueous media. This product is a pre-formulated liposomal version of Rocaglamide which is supplied ready to use in vitro or in vivo. The liposomes are PEGylated for optimal in vivo performance. For preclinical research use only.
Lipid composition PEGylated Liposomes
Liposome Size 70-120 nm
Lipid Molar Concentration 60 mM
Encapsulated Drug Rocaglamide
Drug concentration 4.0 mg/mL (± ~5%)
Inside Buffer 292 mM sucrose, 0.5% DPBS (1X)
Outside Buffer 292 mM sucrose, 0.5% DPBS (1X)
Storage 2 °C to 8 °C (do not freeze), protect from light
Shelf-life At least 1 month
CAS No. 84573-16-0
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