Clipos™ Lificiguat (YC-1) Encapsulated Liposomes
Specifications
Description
|
PEGylated liposomes containing HIF-1α inhibitor Lificiguat (YC-1). Lificiguat (YC-1) is an inhibitor of Hypoxia-inducible factor-1 alpha (HIF-1 alpha). YC-1 also activates soluble guanylyl cyclase (sGC) in (NO)-independent manner. Lificiguat (YC-1) is insoluble in aqueous media. This product is a pre-formulated liposomal version of Lificiguat which is supplied ready to use in vitro or in vivo. The liposomes are PEGylated for optimal in vivo performance. For preclinical research use only. |
Lipid composition
|
PEGylated Liposomes |
Liposome Size
|
70-120 nm |
Lipid Molar Concentration
|
60 mM |
Encapsulated Drug
|
Lificiguat |
Drug concentration
|
2.5 mg/mL |
Inside Buffer
|
292 mM sucrose, 0.5% DPBS (1X) |
Outside Buffer
|
292 mM sucrose, 0.5% DPBS (1X) |
Storage
|
2 °C to 8 °C (do not freeze), protect from light |
Shelf-life
|
At least 1 month |
CAS No.
|
170632-47-0 |
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