Clipos™ Phosphatidylcholine (PC) Liposomes, PEGylated


Catalog:CDEPG-38

Unit Size:2 mL, 10 mL

INQUIRY Datasheet

Specifications
Description Long-circulating, PEGylated drug composite liposomes containing daunorubicin HCl and vincristine sulfate at a 10/1 (mol/mol) ratio. The liposomes are loaded by an ammonium sulfate gradient method, sterilized by submicron filtration, and dispensed aseptically into sterile glass vials. The liposomes are useful for the study of ratiometric dosing with chemotherapeutic agents in preclinical models of cancer, suitable for use in vitro or in vivo.
Lipid composition HSPC/Chol/DSPE-mPEG2000 (56.2/38.5/5.3 molar ratio)
Liposome Size 80-120 nm
Lipid Molar Concentration 30 mM
Encapsulated Drug Daunorubicin, Vincristine
Drug concentration 1.4 mg/mL, 219 μg/mL
Inside Buffer 250 mM Ammonium Sulfate, pH 5.5
Outside Buffer 154 mM NaCl, pH 5.5
Storage 2 °C to 8 °C (do not freeze)
Shelf-life 6 months
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