Abemaciclib metabolite M18 hydrochloride


Abemaciclib metabolite M18 hydrochloride

Abemaciclib metabolite M18 hydrochloride

Catalog:CDMDC12

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Specifications
Synonym LSN3106729 hydrochloride
Common Use Abemaciclib metabolite M18 (LSN3106729) hydrochloride, the metabolite of Abemaciclib, is a CDK inhibitor with antitumor activity. Abemaciclib metabolite M18 hydrochloride and a CRBN ligand have been used to design PROTAC CDK4/6 degrader.
Structure Abemaciclib metabolite M18 hydrochloride
Molecular Weight 531
Purity 0.9801
Molecular Formula C25H29ClF2N8O
Appearance Solid
Storage • 4°C, sealed storage, away from moisture
• In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solubility • DMSO: ≥ 125 mg/mL (235.4 mM)
• H2O: ≥ 100 mg/mL (188.32 mM)
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