Synonym | PROTAC Sirt2-binding moiety 1 |
Common Use | SirReal1-O-propargyl is a selective and highly potent Sirtuin 2 (Sirt2) inhibitor, with an IC50 of 2.4 μM. SirReal1-O-propargyl, the SirReal1-based moiety, binds to the cereblon ligand via a linker to form PROTAC to degrade Sirt2. |
Structure | |
Molecular Weight | 424.54 |
Molecular Formula | C21H20N4O2S2 |
CAS No. | 1862237-99-7 |
Appearance | Solid |
Storage | • 4°C, stored under nitrogen • In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen) |
Catalog: CDMDC01
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