SirReal1-O-propargyl


SirReal1-O-propargyl

SirReal1-O-propargyl

Catalog:CDMDC40

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Specifications
Synonym PROTAC Sirt2-binding moiety 1
Common Use SirReal1-O-propargyl is a selective and highly potent Sirtuin 2 (Sirt2) inhibitor, with an IC50 of 2.4 μM. SirReal1-O-propargyl, the SirReal1-based moiety, binds to the cereblon ligand via a linker to form PROTAC to degrade Sirt2.
Structure SirReal1-O-propargyl
Molecular Weight 424.54
Molecular Formula C21H20N4O2S2
CAS No. 1862237-99-7
Appearance Solid
Storage • 4°C, stored under nitrogen
• In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
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