BMS-1166-N-piperidine-COOH


BMS-1166-N-piperidine-COOH

BMS-1166-N-piperidine-COOH

Catalog:CDMDC42

Unit Size:

INQUIRY Datasheet

Specifications
Common Use BMS-1166-N-piperidine-COOH, the BMS-1166-based moiety, binds to E3 ligase ligand via a linker to form PROTAC PD-1/PD-L1 degrader-1 (HY-131183) to degrade PD-1/PD-L1. BMS-1166 is a potent PD-1/PD-L1 interaction inhibitor with an IC50 of 1.4 nM. BMS-1166 antagonizes the inhibitory effect of PD-1/PD-L1 immune checkpoint on T cell activation.
Structure BMS-1166-N-piperidine-COOH
Molecular Weight 639.14
Purity 0.9726
Molecular Formula C37H35ClN2O6
CAS No. 2447066-00-2
Appearance Solid
Storage • -20°C, sealed storage, away from moisture and light
• In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Related Products
Products
Fill out the form below
to receive a quote

GET A QUOTE

  • (USA)
  • (Europe)
Cookie Policy | Privacy Policy | Copyright © 2024 CD Bioparticles. All rights reserved.
0
Inquiry Basket
Inquiry