Doxorubicin-Hydrazone-Polyethylene glycol-Amine


Doxorubicin-Hydrazone-Polyethylene glycol-Amine

DOX-Hyd-PEG-NH2

Catalog:PHRC475

Unit Size:50 mg, 100 mg

INQUIRY Datasheet

Specifications
Common Use The hydrazone bond is stable in the weak alkali condition, but it can break quickly in the weak acid condition, thus releasing the drug.PEG-DOX, a prodrug of doxorubicin, has multiple advantages: it greatly increases the water solubility of doxorubicin. Moreover, PEG-DOX, a prodrug of doxorubicin, can effectively self assemble to form stable nanoparticles in physiological environment, and the EPR effect of nanodrugs can be used for targeted drug delivery
PEG Molecular Weight 1000 Da
Purity >95%
Appearance Brown/off-white solid or viscous liquid
Storage -20 °C, protected from light and moisture
Stability 1 year
Functional Group Amine
Structure Doxorubicin-Hydrazone-Polyethylene glycol-Amine
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