YGRKKRRQRRRKLSSIESDV


YGRKKRRQRRRKLSSIESDV

Tat-NR2B9c

Catalog:CDCCP23-019L

Unit Size:1 mg, 5 mg, 10 mg, 25 mg, 50 mg, 100 mg

INQUIRY Datasheet

Specifications
Synonym Tat-NR2Bct, NA-1
Common Use Tat-NR2B9c (Tat-NR2Bct; NA-1) is a postsynaptic density-95 (PSD-95) inhibitor, with EC50 values of 6.7 nM and 670 nM for PSD-95d2 (PSD-95 PDZ domain 2) and PSD-95d1, respectively. Tat-NR2B9c disrupts the PSD-95/NMDAR interaction, inhibiting NR2A and NR2B binding to PSD-95 with IC50 values of 0.5 μM and 8 μM, respectively. Tat-NR2B9c also inhibits neuronal nitric oxide synthase (nNOS)/PSD-95 interaction, and possesses neuroprotective efficacy
Structure YGRKKRRQRRRKLSSIESDV
Molecular Weight 2518.88
Purity ≥99%
Molecular Formula C105H188N42O30
CAS No. 500992-11-0
Appearance Solid
Storage Powder: -80 °C, 2 years; -20 °C, 1 year. In solvent: -80 °C, 6 months; -20 °C, 1 month (sealed storage, away from moisture)
Solubility Soluble in water
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