Common Use | Licochalcone B is an extract from the root of Glycyrrhiza uralensis. Licochalcone B inhibits amyloid β (42) self-aggregation (IC50=2.16 μM) and disaggregate pre-formed Aβ42 fibrils, reduce metal-induced Aβ42 aggregation through chelating metal ionsLicochalcone B inhibits phosphorylation of NF-κB p65 in LPS signaling pathway. Licochalcone B inhibits growth and induces apoptosis of NSCLC cells. Licochalcone B specifically inhibits the NLRP3 inflammasome by disrupting NEK7‐NLRP3 interaction |
Structure | |
Molecular Weight | 286.28 |
Purity | ≥99% |
Molecular Formula | C16H14O5 |
CAS No. | 58749-23-8 |
Appearance | Solid |
Storage | 4 °C, protect from light. In solvent : -80 °C, 6 months; -20 °C, 1 month (protect from light) |
Insoluble | Insoluble in H2O |
Solubility | Soluble in DMSO |
Catalog: CDPE23-001-L
Catalog: CDPE23-002-L
Catalog: CDPE23-003-L
Catalog: CDPE23-004-L
Catalog: CDPE23-005-L
Catalog: CDPE23-006-L
Catalog: CDPE23-007-L
Catalog: CDPE23-008-L