Common Use | Tert-Butyl (2-(2-(2-azidoethoxy)ethoxy)ethyl)carbamate (N3-PEG2-NH-BOC), or Boc-protected amine-PEG2-Azide. tBoc-amine can be deprotected by acid (TFA) to free amine, which react with carboxylic acid and its active esters, and isocyanates. It can also react with carbonyl such as ketone and aldehyde. Azide were used to react azide group “click” chemistry in mild condition, which is very useful for bioconjugation. |
Structure | |
PEG Molecular Weight | 274.32 g/mol |
Functional Group | Azide/Boc-protected amine |
Purity | Purity: 97% |
Molecular Formula | C11H22N4O4 |
CAS No. | 950683-55-3 |
Q: How do I deprotect the BOC reagents?
A: Standard BOC Amino Acid Deprotection
• 50% (v/v) TFA/DCM; 50 minutes at room temperature
• Follow with washings with 5% (v/v) DIPEA/DCM to remove TFA
Catalog: CDN-04001
Catalog: CDN-04002
Catalog: CDN-04003
Catalog: CDN-04004
Catalog: CDN-04005
Catalog: CDN-04006
Catalog: CDN-04007
Catalog: CDN-04008