N3-PEG2-NH-BOC


N3-PEG2-NH-BOC

Catalog:CDN-04014

Unit Size:500 mg, 1 g

INQUIRY Datasheet

Specifications
Common Use Tert-Butyl (2-(2-(2-azidoethoxy)ethoxy)ethyl)carbamate (N3-PEG2-NH-BOC), or Boc-protected amine-PEG2-Azide. tBoc-amine can be deprotected by acid (TFA) to free amine, which react with carboxylic acid and its active esters, and isocyanates. It can also react with carbonyl such as ketone and aldehyde. Azide were used to react azide group “click” chemistry in mild condition, which is very useful for bioconjugation.
Structure N3-PEG2-NH-BOC
PEG Molecular Weight 274.32 g/mol
Functional Group Azide/Boc-protected amine
Purity Purity: 97%

Molecular Formula C11H22N4O4
CAS No. 950683-55-3
Q & A

Q: How do I deprotect the BOC reagents?

A: Standard BOC Amino Acid Deprotection
• 50% (v/v) TFA/DCM; 50 minutes at room temperature
• Follow with washings with 5% (v/v) DIPEA/DCM to remove TFA

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