Boc-Amine Alkyne-Poly(ethylene glycol)-COOH

Boc-Amine ALK-PEG-COOH

Catalog:CDN1401

Unit Size:100 mg, 1 g

Specifications

Common Use	Boc-protected amine and alkyne conjugated PEG-carboxylic acid (Boc-amine alkyne-PEG-COOH, Alkyne Boc-amine-PEG-COOH) is a trifunctional PEG derivative, which has Boc-protected amine and alkyne group sharing one end and -COOH group on the other end. tBoc-amine can be deprotected by acid (TFA) to free amine, which react with carboxylic acid and its active esters, and isocyanates. It can also react with carbonyl such as ketone and aldehyde. Alkyne were used to react azide group “click” chemistry in mild condition, which is very useful for bioconjugation. COOH can react with amine or OH containing entities.
Structure
PEG Molecular Weight	1,000 Da
Functional Group	Boc-protected amine/COOH/Alkyne

Q & A

Q: How do I deprotect the BOC reagents?

A: Standard BOC Amino Acid Deprotection
• 50% (v/v) TFA/DCM; 50 minutes at room temperature
• Follow with washings with 5% (v/v) DIPEA/DCM to remove TFA

Related Products

Amine ALK-PEG-COOH
Catalog: CDN1382
Amine ALK-PEG-COOH
Catalog: CDN1383
Amine ALK-PEG-COOH
Catalog: CDN1384
Amine ALK-PEG-COOH
Catalog: CDN1385
Amine ALK-PEG-COOH
Catalog: CDN1386
Amine ALK-PEG-OH
Catalog: CDN1387
Amine ALK-PEG-OH
Catalog: CDN1388
Amine ALK-PEG-OH
Catalog: CDN1389

Products

Fill out the form below
to receive a quote

GET A QUOTE