Common Use | Boc-NH-PEG-COOH is a linear heterobifunctional PEG reagent with one Boc protected amine and one carboxyl. It is a useful crosslinking reagent with a PEG spacer. The protected amine can be regenerated by mild acidic conditions such as TFA or dilute HCl. |
Structure | |
PEG Molecular Weight | 1,000 Da |
Functional Group | Boc-protected amine/COOH |
Q: How do I deprotect the BOC reagents?
A: Standard BOC Amino Acid Deprotection
• 50% (v/v) TFA/DCM; 50 minutes at room temperature
• Follow with washings with 5% (v/v) DIPEA/DCM to remove TFA
Catalog: CDE003
Catalog: CDE004
Catalog: CDN1546
Catalog: CDN1547
Catalog: CDN1548
Catalog: CDN1549
Catalog: CDN1550
Catalog: CDN1551