Common Use | t-Butoxycarbonyl-Amine-PEG-Amine (tBoc-NH-PEG-NH2) is a linear heterobifunctional PEG reagent with Boc protected amine and a free amine. It is a useful crosslinking reagent with a PEG spacer. The free amine typically in the form of TFA or HCl salt can be used to react with carboxyl or NHS ester. The protected amine can be regenerated by mild acidic conditions. |
Structure | |
PEG Molecular Weight | 2,000 Da |
Functional Group | Boc-protected amine/Amine |
Q: How do I deprotect the BOC reagents?
A: Standard BOC Amino Acid Deprotection
• 50% (v/v) TFA/DCM; 50 minutes at room temperature
• Follow with washings with 5% (v/v) DIPEA/DCM to remove TFA
Catalog: CDE003
Catalog: CDE004
Catalog: CDN1546
Catalog: CDN1547
Catalog: CDN1548
Catalog: CDN1549
Catalog: CDN1550
Catalog: CDN1551