tBoc-protected amine-PEG-Amine


tBoc-protected amine-PEG-Amine

tBoc-NH-PEG-NH2

Catalog:CDN1857

Unit Size:1 g, 5 g

INQUIRY Datasheet

Specifications
Common Use t-Butoxycarbonyl-Amine-PEG-Amine (tBoc-NH-PEG-NH2) is a linear heterobifunctional PEG reagent with Boc protected amine and a free amine. It is a useful crosslinking reagent with a PEG spacer. The free amine typically in the form of TFA or HCl salt can be used to react with carboxyl or NHS ester. The protected amine can be regenerated by mild acidic conditions.
Structure tBoc-protected amine-PEG-Amine
PEG Molecular Weight 2,000 Da
Functional Group Boc-protected amine/Amine
Q & A

Q: How do I deprotect the BOC reagents?

A: Standard BOC Amino Acid Deprotection
• 50% (v/v) TFA/DCM; 50 minutes at room temperature
• Follow with washings with 5% (v/v) DIPEA/DCM to remove TFA

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