Common Use | Methoxy poly(ethylene glycol)-Iodolacetyl (MPEG-IA) is one type of linear monofunctional PEG acid reagents. PEG-IA can be used to react with thiol groups.Haloacetyl reaction chemistry: The most commonly used haloacetyl crosslinkers contain an iodoacetyl or a bromoacetyl group. Haloacetyls react with sulfhydryl groups at physiologic pH. The reaction of the iodoacetyl group proceeds by nucleophilic substitution of iodine with a sulfur atom from a sulfhydryl group, resulting in a stable thioether linkage. |
Structure | |
PEG Molecular Weight | 2,000 Da |
Functional Group | Methoxy/Iodoacetyl |
Q: What are the storage conditions for the product?
A: The product should be stored under nitrogen or argon at low temperature (-20℃). This product should be kept away from light.