1,2-Dioleoyl-sn–glycero-3-phosphoethanolamine (DOPE)-polyethylene glycol-amine

DOPE-PEG-Amine

Catalog:CDN2139

Unit Size:100 mg, 500 mg, 1 g

Specifications

Common Use	1,2-Dioleoyl-sn–glycero-3-phosphoethanolamine (DOPE)-polyethylene glycol-amine (DOPE-PEG-Amine, DOPE-PEG-NH2) is a linear heterobifunctional PEGylation reagent with an unsaturated DOPE phospholipid and an amine. DOPE-PEG-NH2 is used to modify liposome surface with biomolecules containing amine reactive groups (NHS, thiolate). It is a useful self-assembling reagent to prepare grafted or PEGylated liposome or micelle while also providing an amine group for bioconjugation. It is often used in targeted drug delivery with the lipid bilayer to improve drug solubility, the PEG to provide stealth property, extend circulation half-life and reduce non-specific protein binding or cell adhesion, and the amine group to bioconjugate targeting molecules including antibody, aptamer, protein, and peptide.
Structure
PEG Molecular Weight	5,000 Da
Functional Group	DOPE/Amine

Q & A

Q: What are the storage conditions for the product?

A: The product should be stored under nitrogen or argon at low temperature (-20℃). This product should be kept away from light.