MAL-PEG4-Val-Cit-PAB-PNP


MAL-PEG4-Val-Cit-PAB-PNP

Catalog:CDPB-041350

Unit Size:50 mg, 100 mg, 250 mg, 1 g

INQUIRY Datasheet

Specifications
Common Use Linker for Antibody-Drug-Conjugation (ADC). The Val-Cit will specifically be cleaved by catepsin B. As this enzyme is only present in the lysosome the ADC payload will be release only in the cell. Azido group will react with DBCO, BCN or other Alkyne group through click chemistry, PEG spacer increases aqueous solubility.
Structure MAL-PEG4-Val-Cit-PAB-PNP
PEG Molecular Weight 871.9 g/mol
Functional Group Maleimide/PNP
Purity 97%
Molecular Formula C40H53N7O15
CAS No. 2112738-09-5
Storage -20°C
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