Description | The fluorescent control liposomes contain the lipophilic Near IR dye DiR incorporated in the bilayers. It is used for tracking the cellular uptake of the liposomes in vitro and in vivo by common methods like confocal, FACS, NIR imaging etc. The near IR fluorescent, lipophilic carbocyanine DiOC18(7) ("DiR") is weakly fluorescent in water but highly fluorescent and quite photostable when incorporated into membranes. The sulfonate groups incorporated into this DiI analog improves water solubility. It has an extremely high extinction coefficient and short excited-state lifetimes (~1 nanosecond) in lipid environments. |
Lipid composition | DOPC/Cholesterol (54/45 molar ratio) |
Liposome Size | 100 nm (90-120 nm) |
Lipid Molar Concentration | 50 mM (50-55 mM) |
Fluorophore | DiR |
Fluorophore Concentration | 0.5 mM (0.51 mg/mL) |
Excitation | 750 nm |
Emission | 780 nm |
Buffer | 10% sucrose, 20mM HEPES, pH 7.5 ± 0.2 |
Storage | 2-8 °C |
Shelf-life | 6 months guaranteed for unopened vials. |
Product Name | Catalog | Lipid composition | Liposome Size | Price |
---|---|---|---|---|
Clipos™ DiI labeled Phosphatidylcholine (PC) Liposomes | CDL6001F-DI | DOPC/Cholesterol (54/45 molar ratio) | 100 nm (90-120 nm) | INQUIRY |
Clipos™ DiD labeled Phosphatidylcholine (PC) Liposomes | CDL6001F-DD | DOPC/Cholesterol (54/45 molar ratio) | 100 nm (90-120 nm) | INQUIRY |
Clipos™ DiO labeled Phosphatidylcholine (PC) Liposomes | CDL6001F-DO | DOPC/Cholesterol (54/45 molar ratio) | 100 nm (90-120 nm) | INQUIRY |
Clipos™ DiA Labeled Phosphatidylcholine (PC) Liposomes | CDL6001F-DA | DOPC/Cholesterol (54/45 molar ratio) | 100 nm (90-120 nm) | INQUIRY |
Clipos™ Dansyl Labeled Phosphatidylcholine (PC) Liposomes | CDL6001F-D | DOPC/Cholesterol/Dansyl- DOPE (54/45/1 molar ratio) | 100 nm (90-120 nm) | INQUIRY |
Clipos™ Fluorescein Labeled Phosphatidylcholine (PC) Liposomes, Non PEGylated | CDL6001F3-F | DOPC/Cholesterol/F-DHPE (54/45/1 molar ratio) | 280 nm (250-320 nm) | INQUIRY |
Clipos™ Fluorescein Labeled Phosphatidylcholine (PC) Liposomes, Non PEGylated | CDL6001F-F | DOPC/Cholesterol/F-DHPE (54/45/1 molar ratio) | 100 nm (90-120 nm) | INQUIRY |
Clipos™ Fluorescein Labeled Phosphatidylcholine (PC) Liposomes, Non PEGylated | CDL6001F2-F | DOPC/Cholesterol/Fluorescein-DHPE (54/45/1 molar ratio) | 230 nm (200-250 nm) | INQUIRY |