Clipos™ Control of Doxorubicin Encapsulated Liposomes, PEGylated

Catalog:CDEDOX-1013

Unit Size:2 mL, 5 mL

INQUIRY Datasheet

Specifications
Description This is a control formulation for PEGylated doxorubicin liposome. The formulation is similar to PEGylated doxorubicin liposome in size and lipid composition, but it does not contain doxorubicin drug. The formulation is for research purposes only and for the injection to laboratory animals. The formulation is made in ammonium sulfate gradient and it is ready for injection.
Lipid composition HSPC/Cholesterol/DSPE-PEG(2000) (57/38/5 molar ratio)
Liposome Size 100 nm
Lipid Mass Concentration 15.96 mg/mL
Lipid Molar Concentration 21.62 mM
Functional Group Plain
Appearance The product is a white translucent liquid made of nano size unilamellar liposomes. Usually, due to the small size of liposomes, no settling will occur in the bottom of the vial. The liposomes are packaged in an amber vial.
Inside Buffer Ammonium Sulfate, pH 6.5
Outside Buffer Histidine/Sucrose Buffer, pH 6.5
Storage Should always be stored at in the dark at 4 °C, except when brought to room temperature for brief periods prior to animal dosing. DO NOT FREEZE. If the suspension is frozen, the encapsulated drug can be released from the liposomes thus limiting its effectiveness. In addition, the size of the liposomes will also change upon freezing and thawing.
Shelf-life 4 months.
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