Description | HSPC/CHOL/mPEG2000-DSPE (56.2/38.5/5.3 mol/mol) liposomes with ammonium gradient is the original lipid copmposition used for liposomal doxorubicin HCl. This lipid composition is a formulator's choice in pharmaceutical/biotech industry for both formulation feasibility studies and liposomal product development. HSPC is essentially equivalent to DSPC (HSPC contains about 85 % DSPC and 15% DPPC). The main advantages for using HSPC are its lower cost and availability of GMP quality raw materials. |
Lipid composition | HSPC/Cholesterol/mPEG2000-DSPE (56.2/38.5/5.3 molar ratio) |
Liposome Size | 100 nm (95-120 nm) |
Lipid Molar Concentration | 60 mM (60-70 mM) |
Inside Buffer | 10% sucrose, 20mM sodium PO4, pH 6.5 ± 0.2 |
Outside Buffer | 10% sucrose, 20mM sodium PO4, pH 6.5 ± 0.2 |
Storage | 2-8 °C |
Shelf-life | 6 months |
Product Name | Catalog | Lipid composition | Liposome Size | Price |
---|---|---|---|---|
Clipos™ Diether Phosphatidylcholine (PC) Liposomes | CDECDEE-1610 | 100% 12/0 Diether PC | 100 nm | INQUIRY |
Clipos™ Diether Phosphatidylcholine (PC) Liposomes, Lyophilized | CDELDE-1310 | 100% 12/0 Diether PC | 100 nm (after hydration) | INQUIRY |
Clipos™ Saturated Phosphatidylcholine (PC) Liposomes | CDECHP-1553 | 100% 12/0 PC (DLPC) | 100 nm | INQUIRY |
Clipos™ Diether Phosphatidylcholine (PC) Liposomes | CDECDEE-1611 | 100% 13/0 Diether PC | 100 nm | INQUIRY |
Clipos™ Diether Phosphatidylcholine (PC) Liposomes, Lyophilized | CDELDE-1311 | 100% 13/0 Diether PC | 100 nm (after hydration) | INQUIRY |
Clipos™ Saturated Phosphatidylcholine (PC) Liposomes | CDECHP-1554 | 100% 13/0 PC | 100 nm | INQUIRY |
Clipos™ Diether Phosphatidylcholine (PC) Liposomes | CDECDEE-1612 | 100% 14/0 Diether PC | 100 nm | INQUIRY |
Clipos™ Diether Phosphatidylcholine (PC) Liposomes, Lyophilized | CDELDE-1312 | 100% 14/0 Diether PC | 100 nm (after hydration) | INQUIRY |