Clipos™ Doxorubicin HCl Encapsulated Liposomes, PEGylated

Catalog:CDL3001B-D2

Unit Size:2 mL

INQUIRY Datasheet

Specifications
Description Doxorubicin HCl is loaded into PEGylated liposomes with ammonium gradient by the active loading approach. The liposomes are prepared to high quality with consistent lot-lot characteristics. Narrow particle size distribution and high drug encapsulation efficiency. Note we also carry a high drug concentration (4.0 mg/mL) version of this product (CDL30204B-D).
Lipid composition HSPC/Cholesterol/mPEG2000-DSPE (56.2/38.5/5.3 molar ratio)
Liposome Size 85 nm (80-90 nm)
Lipid Molar Concentration 20 mM
Functional Group Plain
Encapsulated Drug Doxorubicin HCl
Drug concentration 2 mg/mL
Encapsulation efficiency > 95% (typically 98%)
Loading Battery 250 mM ammonium sulfate
Outside Buffer 10% sucrose, 10 mM histidine, pH 6.5
Storage 2-8 °C
Shelf-life 6 months
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