Clipos™ Control of Neutral Clodronate Encapsulated Liposomes, DiA Labeled
Specifications
Description
|
The fluorescent control liposomes contain the lipophilic dye DiA incorporated in the bilayers. It has comparable physical and chemical attributes as for the Clodronate Encapsulated Liposomes except no active is encapsulated inside. It is used for tracking the cellular uptake of the liposomes by common methods like confocal, FACS, etc. The lipophilic aminostyryl probe DiA inserts into liposome bilayers with its two alkyl tails and its fluorophore oriented parallel to the phospholipid acyl chain. When this dialkylaminostyryl probe binds to membranes, it exhibits a strong fluorescence enhancement; its fluorescence in water is minimal. |
Lipid composition
|
PC/Cholesterol |
Fluorophore
|
DiA |
Fluorophore Concentration
|
0.15 mM (0.12 mg/mL) |
Excitation
|
456 nm |
Emission
|
590 nm |
Storage
|
2-8 °C |
Shelf-life
|
6 months for unopened vials |
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