Poly(D,L-lactide-co-glycolide), Acid-terminated

Poly(D,L-lactide-co-glycolide), Acid-terminated

PLGA, Acid-terminated

Catalog:CDPOLY01

Unit Size:1 g, 10 g

INQUIRY Datasheet

Specifications
Synonym PDLGA, PLGA, DL-PLGA
Common Use Poly(DL-lactide-co-glycolide) (PLGA) is a well-established biodegradable polymer used in medical devices and drug delivery applications. In comparison to poly(L-lactide) (PLLA), PLGA offers control over degredation rate and reduced glass transition temperatures (by increasing glycolide content). The control of these properties makes PLGA especially well suited for applications where medical devices are only needed for weeks (e.g. drug delivery). Acid-terminated PLGA can be soluble in dichloromethane (DCM), tetrahydrofuran (THF), ethyl acetate, acetone. Acid-terminated PLGA allows for easy conjugation to drugs with nucleophilic functionalities. Glass Transition Temp. (Tg): 45-50°C.
Structure Poly(D,L-lactide-co-glycolide), Acid-terminated
PLGA Molecular Weight 10,000-18,000 Da
Monomer Ratio LA:GA 50:50
Functional Group Acid
Viscosity 0.15 - 0.25 dL/g (25°C; CHCl3, 1.0 g/dL)
CAS No. 26780-50-7
Storage Protect from moisture. Store at -20°C.
Surface Charge Density > 6 (mg KOH)/g
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