Description
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RGD sequences are motifs on extracellular matrix proteins promoting adhesion to cellular integrin receptors. The Scrambled RGD Peptide contains a scrambled RGD motif and a thiol on a N-terminal ysteine residue. The thiol is used to immobilize the peptide on maleimide polymers in 3D Cell Culture Hydrogels. The immobilized peptide can be used as a control to determine the specificity of cell adhesion caused by a genuine RGD peptide (e.g. RGD Peptide). Peptide sequence: Acetyl-Cys-Doa1-Doa-Gly-Arg-Asp-Gly-Ser-Pro-NH2. Intended for research use only. Not for use in human therapeutic or diagnostic applications. Doa: 8-amino-3,6-dioxaoctanoic acid |
Storage
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-20°C to -80°C |
Reconstitution
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Briefly centrifuge to make sure that entire product is on the bottom of the tube. Add 48 µL sterile water to dissolve content at a concentration of 20 mmol/L. Store reconstituted product at -20°C or -80°C. |
Form
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Powder |
Purity
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>90% (HPLC) |
Formula Weight
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1022 g/mol |
Solubility
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20 mmol/L in water |
Applications Note
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Cell adhesion control peptide. Covalent attachment to maleimide-polymer in 3D Cell Culture Hydrogels. For control of specificity of cell adhesion to RGD peptide. |