ROS (Reactive Oxygen Species) response copolymers have shown great potential in the field of drug delivery. These copolymers can undergo changes in their structure, shape, or properties in response to the presence of ROS, which makes them attractive for designing controlled drug release systems. By incorporating ROS-responsive moieties into the polymer chains, such as thiols or disulfide bonds, the copolymers can be designed to undergo cleavage or degradation in the presence of ROS. The release of the drug payload can be triggered specifically in those ROS-rich environments, allowing for site-specific drug delivery and minimizing off-target effects. Their ability to respond to ROS levels provides an opportunity for targeted and controlled release of drugs, enabling more effective treatments with reduced side effects.