Rapid-Released Microneedle Patches-Based Drug Delivery System

Microneedle patches have emerged as a promising drug delivery technology due to their ability to overcome several limitations associated with traditional drug delivery methods. CD Bioparticles, a company with over 20 years of experience in the formulation industry, is at the forefront of developing microneedle patches for drug delivery.

Figure 1. Rapid-Released Microneedle Patches.

3D Printing Technology

CD Bioparticles utilizes 3D printing technology to manufacture microneedle patches with precise dimensions and geometries. This technology enables the production of complex microneedle arrays that can deliver drugs to specific depths and locations in the skin. Compared to traditional methods of manufacturing membrane devices, 3D printing technology has the ability to produce microneedles quickly and efficiently, with controlled quality. Additionally, the use of 3D printing technology allows for the customization of microneedle patches to fit the specific needs of individual patients, enhancing the accuracy and efficiency of drug delivery. Notably, our 3D printing technology to produce skinny-waist shaped microneedles allows for a significant increase in bioavailability by expanding the microneedle front end.

Figure 2. The process of making microneedle patches with 3D printing technology.^[1]

Manufacturing Capability and Quality

CD Bioparticles has a state-of-the-art manufacturing facility that is equipped with the latest technologies to produce high-quality microneedle patches. Our manufacturing processes adhere to strict quality control guidelines to ensure that our products meet the highest standards. Our quality assurance team conducts rigorous testing and analysis of all products to ensure their safety and efficacy.

Wide Coverage of API

The choice of API which can be loaded into the patch is critical in the development of microneedle patches for drug delivery. Our technology is suitable for dozens or even hundreds of drugs, not limited to individual or a few products. Our research and development pipeline includes several protein microneedle and dozens of peptide drugs at different stages of basic research to industrial development. And the technology can greatly preserve the activity of the biological API.

CD Bioparticles works closely with clients to ensure that the API selected is suitable for microneedle delivery. Our team of experts has extensive experience in formulating APIs for microneedle delivery, and we can recommend the best formulation based on the specific requirements of our clients.

Also, we have the capability to produce microneedles with different drug release profiles, such as zero-order and first-order release kinetics. Our team of experienced scientists and engineers can work with clients to develop custom formulations that meet their specific needs.

Our Microneedle Patches Advantages

CD Bioparticles is a leading provider of rapid-released microneedles, with a proven track record of success in the industry. Our 3D printing technology allows us to produce high-quality microneedle patches with a range of APIs, and our experienced team of professionals is dedicated to providing our clients with the best possible service. Whether you are looking for assistance with formulation development, scale-up and manufacturing, or quality control, CD Bioparticles is the ideal.

• No mold limitation, stable batch production
• Rapid onset of action with >20% bioavailability of proteins and peptides
• 3D printed waist-slimming shaped microneedle with increased dermal contact to enhance transdermal high absorption rate

Quotations and Ordering

Reference

1. Wang Z, et al.; Shrinking Fabrication of a Glucose-Responsive Glucagon Microneedle Patch. Advanced Science. 2022, 9: 2203274-2203281.