Dendrimers

Dendrimers are polymer molecules with a three-dimensional network. They are almost monodisperse macromolecules with highly aligned structures consisting of dendritic arms or branches built around a small molecule or linear polymer core. Their dendritic branching structure is unique and has been explored as a targeted drug delivery system for various diseases in the field of nanomedicine. Dendrimers consist of three components in their structure, including an initial core (starting atoms), an inner layer with repeating units, and an outer. Dendrimers have precise molecular structures whose molecular weight, size, and number of branches can be easily controlled. Dendrimers are generally symmetrical around the core and are available for a large number of functional groups present on the surface. Because dendrimers have multiple end groups and multiple chemical structures, they allow for the conjugation of multiple drugs, especially antineoplastic drugs using various cleavable linkers. Multifunctional dendrimers carry antitumor drugs on their surfaces and can also be modified by solubilizing functions and tumor-targeting ligands.

CD Bioparticles offers dendrimer polymers of varying molecular weights for drug discovery research. In addition, we offer dendrimer polymers modified with acetylene, ammonium, azide, carboxyl, fluorescent rhodamine, hydroxyl, NHBOC and protected amine groups.

PAMAM-50% C12-G4

Catalog: CDPFD23-128

MW: 26010.54 g/mol

Core: Ethylenediamine

Number of Surface Groups: 64

Generation: 4

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PAMAM-G0

Catalog: CDPFD23-095

MW: 436.28 g/mol

Core: Ethylenediamine

Number of Surface Groups: 4

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PAMAM-G0-OH

Catalog: CDPFD23-113

Core: Ethylenediamine

Number of Surface Groups: 4

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PAMAM-G0.5

Catalog: CDPFD23-096

MW: 1269.04 g/mol

Core: Ethylenediamine

Number of Surface Groups: 8

Generation: 0.5

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PAMAM-G1

Catalog: CDPFD23-097

MW: 1429.85 g/mol

Core: Ethylenediamine

Number of Surface Groups: 8

Generation: 1

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PAMAM-G1-COOH

Catalog: CDPFD23-121

MW: 2230 g/mol

Core: Ethylenediamine

Number of Surface Groups: 8

Generation: 1

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PAMAM-G1-OH

Catalog: CDPFD23-114

MW: 1438 g/mol

Core: Ethylenediamine

Number of Surface Groups: 8

Generation: 1

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PAMAM-G1.5

Catalog: CDPFD23-098

MW: 2934.56 g/mol

Core: Ethylenediamine

Number of Surface Groups: 16

Generation: 1.5

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PAMAM-G10

Catalog: CDPFD23-112

MW: 934685.09 g/mol

Core: Ethylenediamine

Number of Surface Groups: 4096

Generation: 10

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PAMAM-G2

Catalog: CDPFD23-099

MW: 3256.18 g/mol

Core: Ethylenediamine

Number of Surface Groups: 16

Generation: 2

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PAMAM-G2-COOH

Catalog: CDPFD23-122

MW: 4856 g/mol

Core: Ethylenediamine

Number of Surface Groups: 16

Generation: 2

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PAMAM-G2-OH

Catalog: CDPFD23-115

MW: 3271.93 g/mol

Core: Ethylenediamine

Number of Surface Groups: 16

Generation: 2

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PAMAM-G2.5

Catalog: CDPFD23-100

MW: 6265.60 g/mol

Core: Ethylenediamine

Number of Surface Groups: 32

Generation: 2.5

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PAMAM-G3

Catalog: CDPFD23-101

MW: 6908.84 g/mol

Core: Ethylenediamine

Number of Surface Groups: 32

Generation: 3

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PAMAM-G3-COOH

Catalog: CDPFD23-123

MW: 10109 g/mol

Core: Ethylenediamine

Number of Surface Groups: 32

Generation: 3

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PAMAM-G3-OH

Catalog: CDPFD23-116

MW: 6940.35 g/mol

Core: Ethylenediamine

Number of Surface Groups: 32

Generation: 3

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PAMAM-G3.5

Catalog: CDPFD23-102

MW: 12927.69 g/mol

Core: Ethylenediamine

Number of Surface Groups: 64

Generation: 3.5

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PAMAM-G4

Catalog: CDPFD23-103

MW: 14214.17 g/mol

Core: Ethylenediamine

Number of Surface Groups: 64

Generation: 4

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PAMAM-G4-COOH

Catalog: CDPFD23-124

MW: 20615 g/mol

Core: Ethylenediamine

Number of Surface Groups: 64

Generation: 4

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PAMAM-G4-OH

Catalog: CDPFD23-117

MW: 14277.19 g/mol

Core: Ethylenediamine

Number of Surface Groups: 64

Generation: 4

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